Figure 1: Cell death after Mycobacterium tuberculosis transposon mutant infection. THP-1 cells were infected at a multiplicity of infection of 10 with transposon mutants, H37Rv, left untreated or treated with staurosporine. Cells were harvested and fixed 4-days postinfection, terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) stained, and analyzed via flow cytometry. Data represent a compilation of four experiments. Note: FID = fail to inhibit cell death; STS = staurosporine. *p < .05.