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ORIGINAL ARTICLE
Year : 2018  |  Volume : 7  |  Issue : 2  |  Page : 148-151

The problem of resistance in Mycobacterium tuberculosis may be underestimated in Africa


1 Department of Veterinary Public Health and Preventive Medicine, University of Ibadan, Ibadan, Nigeria
2 Department of Microbiology, University of Ibadan, Ibadan, Nigeria
3 Department of Medicine, Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
4 National Tuberculosis Reference Laboratory, National Institute for Public Health and the Environment, BA Bilthoven, The Netherlands

Correspondence Address:
Simeon I B. Cadmus
Department of Veterinary Public Health and Preventive Medicine, University of Ibadan, Ibadan
Nigeria
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijmy.ijmy_29_18

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Background: The true burden of tuberculosis (TB) and particularly multidrug-resistant (MDR) TB in Sub-Saharan Africa has remained underestimated. Methods: We investigated drug susceptibility profile and genetic diversity of Mycobacterium tuberculosis isolates collected from confirmed tuberculosis patients in Ibadan, southwestern Nigeria. Results: We confirmed that from 74 randomly selected Mycobacterium tuberculosis isolates available for drug susceptibility testing in Ibadan, in 2011, 13.5% of them were MDR-TB. Conclusions: This figure is obviously above the national and World Health Organization figures.


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