Close
  Indian J Med Microbiol
 

Figure 4: Inhibitory activity of the compounds on the growth of Mycobacterium smegmatis. (a) The growth inhibition was monitored by OD595at 0 and 24 h after the treatment using compounds: left, INH (as a positive control); center, KES4; and right, KEN1. The concentration of the tested compounds was 100 μM. All experiments were performed in quadruplicate: nS: Not significant; *P < 0.05. (b) Dose-dependent effects of KES4 (left) and KEN1 (right) on the growth of Mycobacterium smegmatis. The inhibition of mycobacterial growth was monitored by OD595at 24 h after treatment with the compounds. The IC50value of isoniazid (positive control) is 5.4 μM

Figure 4: Inhibitory activity of the compounds on the growth of <i>Mycobacterium smegmatis</i>. (a) The growth inhibition was monitored by OD<sub>595</sub>at 0 and 24 h after the treatment using compounds: left, INH (as a positive control); center, KES4; and right, KEN1. The concentration of the tested compounds was 100 μM. All experiments were performed in quadruplicate: nS: Not significant; *<i>P</i> < 0.05. (b) Dose-dependent effects of KES4 (left) and KEN1 (right) on the growth of <i>Mycobacterium smegmatis</i>. The inhibition of mycobacterial growth was monitored by OD<sub>595</sub>at 24 h after treatment with the compounds. The IC<sub>50</sub>value of isoniazid (positive control) is 5.4 μM