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  Indian J Med Microbiol
 

Figure 5: Predicted specific interactions of KEM4 (a) and KEN1 (b) with the active site of mtInhA: The green lines between the hydrogen atoms (between the C-ring and B-ring) and Phe149 indicate CH-π interaction. The orange curves surrounding the 2-furoyl group of KES4 or the 2-thienyl group of KEN1 indicate hydrophobic interactions with Leu218. The blue lines between the D-ring proximal carbonyl groups and Tyr158 indicate hydrogen bonds

Figure 5: Predicted specific interactions of KEM4 (a) and KEN1 (b) with the active site of mtInhA: The green lines between the hydrogen atoms (between the C-ring and B-ring) and Phe149 indicate CH-π interaction. The orange curves surrounding the 2-furoyl group of KES4 or the 2-thienyl group of KEN1 indicate hydrophobic interactions with Leu218. The blue lines between the D-ring proximal carbonyl groups and Tyr158 indicate hydrogen bonds